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acalabrutinib increases effects of aspirin by anticoagulation. Modify Therapy/Monitor Closely. Coadministration of acalabrutinib with antiplatelets or anticoagulants may even further raise risk of hemorrhage.Dipyridamole: Inhibits uptake of adenosine into platelets, endothelial cells, and erythrocytes Mixture of aspirin and dipyridamole generates a